Works well with Mom's Knife, as you can melee damage enemies without being damaged.

For thou art with me thy rod and thy staff, they comfort me.Dogma's secret lines (being a reading of. Yea though I walk through the valley of the shadow of death, I will fear no evil. He leadeth me, in the paths of righteousness for His Name's sake. You can essentially gain soul hearts by picking up The Mark or The Pact. He maketh me to lie down in green pastures.

Using this item as ? and then picking up a devil room item will not cost you any soul hearts.

Works considerably well with the IV Bag because of the quick recharge time, allowing for a lot of money to be gathered without taking damage.

Activating the item and using your tears at short range will safely deal massive damage.

IPECAC works very well with this item.

The story begins when God says to Abraham, Take. Write the second section of your page here. There are many verbal connections and literary parallels between this chapter and the previous narrative. Judas' Shadow is an item found in The Binding of Isaac: Rebirth Write the first section of your page here.

The Virus works extremely well with this item as walking into enemies while invincible will still apply the poison and damage effects, being able to cause massive damage to high health enemies such as Isaac and ? during the invincibility duration. Chapter 22 is often noted as the climax of the whole story of Abraham, and it is thoroughly integrated with what has gone on before.

As with most activated items, items such as Habit, 9 Volt and The Battery decrease the charge time, increasing the effectiveness of this item.

Changing the room while the shield is up will remove the effect.

As with all invincibility granting items, this item allows for farming of Blood Donation Machines and Devil Beggars, free use of Sacrifice Rooms, and free entrance to or exit from the Curse Room while active.

Upon activation, Isaac raises the book and gains a temporary 10 second (which translates to 300 frames) invincibility from all damage, barring the loss of heart containers.

Binding of isaac my shadow